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==The apo-form UDP-glucose 6-dehydrogenase==
==The apo-form UDP-glucose 6-dehydrogenase==
<StructureSection load='3phl' size='340' side='right' caption='[[3phl]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3phl' size='340' side='right'caption='[[3phl]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3phl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PHL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PHL FirstGlance]. <br>
<table><tr><td colspan='2'>[[3phl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae_NTUH-K2044 Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PHL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PHL FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dli|1dli]], [[3pid|3pid]], [[3pjg|3pjg]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KP1_3701, ugd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 Klebsiella pneumoniae])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3phl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3phl OCA], [https://pdbe.org/3phl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3phl RCSB], [https://www.ebi.ac.uk/pdbsum/3phl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3phl ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-glucose_6-dehydrogenase UDP-glucose 6-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.22 1.1.1.22] </span></td></tr>
</table>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3phl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3phl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3phl RCSB], [http://www.ebi.ac.uk/pdbsum/3phl PDBsum]</span></td></tr>
== Function ==
<table>
[https://www.uniprot.org/uniprot/A0A0J9WZA6_KLEPN A0A0J9WZA6_KLEPN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.,Chen YY, Ko TP, Lin CH, Chen WH, Wang AH J Struct Biol. 2011 Sep;175(3):300-10. Epub 2011 Apr 23. PMID:21536136<ref>PMID:21536136</ref>
Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.,Chen YY, Ko TP, Lin CH, Chen WH, Wang AH J Struct Biol. 2011 Sep;175(3):300-10. Epub 2011 Apr 23. PMID:21536136<ref>PMID:21536136</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3phl" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Klebsiella pneumoniae]]
[[Category: Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]]
[[Category: UDP-glucose 6-dehydrogenase]]
[[Category: Large Structures]]
[[Category: Chen, W H.]]
[[Category: Chen WH]]
[[Category: Chen, Y Y.]]
[[Category: Chen YY]]
[[Category: Ko, T P.]]
[[Category: Ko TP]]
[[Category: Lin, C H.]]
[[Category: Lin CH]]
[[Category: Wang, A H.J.]]
[[Category: Wang AHJ]]
[[Category: Dehydrogenase]]
[[Category: Oxidoreductase]]
[[Category: Rossmann fold]]
Retrieved from "https://proteopedia.org/3phl"