3rhc: Difference between revisions

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==Crystal structure of the holo form of glutaredoxin C5 from Arabidopsis thaliana==
==Crystal structure of the holo form of glutaredoxin C5 from Arabidopsis thaliana==
<StructureSection load='3rhc' size='340' side='right' caption='[[3rhc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='3rhc' size='340' side='right'caption='[[3rhc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3rhc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RHC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RHC FirstGlance]. <br>
<table><tr><td colspan='2'>[[3rhc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RHC FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fz9|3fz9]], [[3rhb|3rhb]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GRXC5, At4g28730, F16A16.160 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rhc OCA], [https://pdbe.org/3rhc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rhc RCSB], [https://www.ebi.ac.uk/pdbsum/3rhc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rhc ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rhc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rhc RCSB], [http://www.ebi.ac.uk/pdbsum/3rhc PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/GRXC5_ARATH GRXC5_ARATH] Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. Can assemble a [2Fe-2S] cluster, but cannot transfer it to an apoferredoxin.<ref>PMID:21632542</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Arabidopsis chloroplastic glutaredoxin C5 as a model to explore the molecular determinants for iron-sulfur cluster binding into glutaredoxins.,Couturier J, Stroher E, Albetel AN, Roret T, Muthuramalingam M, Tarrago L, Seidel T, Tsan P, Jacquot JP, Johnson MK, Dietz KJ, Didierjean C, Rouhier N J Biol Chem. 2011 Jun 1. PMID:21632542<ref>PMID:21632542</ref>
Arabidopsis chloroplastic glutaredoxin C5 as a model to explore the molecular determinants for iron-sulfur cluster binding into glutaredoxins.,Couturier J, Stroher E, Albetel AN, Roret T, Muthuramalingam M, Tarrago L, Seidel T, Tsan P, Jacquot JP, Johnson MK, Dietz KJ, Didierjean C, Rouhier N J Biol Chem. 2011 Jun 1. PMID:21632542<ref>PMID:21632542</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3rhc" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Couturier, J.]]
[[Category: Large Structures]]
[[Category: Didierjean, C.]]
[[Category: Couturier J]]
[[Category: Jacquot, J P.]]
[[Category: Didierjean C]]
[[Category: Roret, T.]]
[[Category: Jacquot JP]]
[[Category: Rouhier, N.]]
[[Category: Roret T]]
[[Category: Tsan, P.]]
[[Category: Rouhier N]]
[[Category: Glutaredoxin]]
[[Category: Tsan P]]
[[Category: Oxidoreductase]]
[[Category: Thiol-disulfide oxidoreductase]]
[[Category: Thioredoxin fold]]