3s3w: Difference between revisions

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==Structure of chicken acid-sensing ion channel 1 at 2.6 a resolution and ph 7.5==
==Structure of chicken acid-sensing ion channel 1 at 2.6 a resolution and ph 7.5==
<StructureSection load='3s3w' size='340' side='right' caption='[[3s3w]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='3s3w' size='340' side='right'caption='[[3s3w]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3s3w]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S3W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S3W FirstGlance]. <br>
<table><tr><td colspan='2'>[[3s3w]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S3W FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ACCN2, ASIC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 Gallus gallus])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s3w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3s3w RCSB], [http://www.ebi.ac.uk/pdbsum/3s3w PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s3w OCA], [https://pdbe.org/3s3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s3w RCSB], [https://www.ebi.ac.uk/pdbsum/3s3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s3w ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ASIC1_CHICK ASIC1_CHICK] Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride (By similarity).<ref>PMID:16002453</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1.,Dawson RJ, Benz J, Stohler P, Tetaz T, Joseph C, Huber S, Schmid G, Hugin D, Pflimlin P, Trube G, Rudolph MG, Hennig M, Ruf A Nat Commun. 2012 Jul 3;3:936. doi: 10.1038/ncomms1917. PMID:22760635<ref>PMID:22760635</ref>
Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1.,Dawson RJ, Benz J, Stohler P, Tetaz T, Joseph C, Huber S, Schmid G, Hugin D, Pflimlin P, Trube G, Rudolph MG, Hennig M, Ruf A Nat Commun. 2012 Jul 3;3:936. doi: 10.1038/ncomms1917. PMID:22760635<ref>PMID:22760635</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3s3w" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Ion channels|Ion channels]]
*[[Ion channels 3D structures|Ion channels 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Benz, J.]]
[[Category: Large Structures]]
[[Category: Dawson, R J.P.]]
[[Category: Benz J]]
[[Category: Hennig, M.]]
[[Category: Dawson RJP]]
[[Category: Huber, S.]]
[[Category: Hennig M]]
[[Category: Huegin, D.]]
[[Category: Huber S]]
[[Category: Joseph, C.]]
[[Category: Huegin D]]
[[Category: Pflimlin, P.]]
[[Category: Joseph C]]
[[Category: Rudolph, M G.]]
[[Category: Pflimlin P]]
[[Category: Ruf, A.]]
[[Category: Rudolph MG]]
[[Category: Schmid, G.]]
[[Category: Ruf A]]
[[Category: Stohler, P.]]
[[Category: Schmid G]]
[[Category: Tetaz, T.]]
[[Category: Stohler P]]
[[Category: Trube, G.]]
[[Category: Tetaz T]]
[[Category: Acid-sensing]]
[[Category: Trube G]]
[[Category: Cell membrane]]
[[Category: Glycoprotein]]
[[Category: Ion channel]]
[[Category: Ion transport]]
[[Category: Membrane]]
[[Category: Membrane glycoprotein]]
[[Category: Membrane protein]]
[[Category: Sodium channel]]
[[Category: Sodium transport]]
[[Category: Transmembrane]]
[[Category: Transport]]
[[Category: Transport protein]]

Latest revision as of 10:25, 6 November 2024

Structure of chicken acid-sensing ion channel 1 at 2.6 a resolution and ph 7.5

3s3w, resolution 2.60Å

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