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==Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis from trigonal partially dehydrated crystal==
==Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis from trigonal partially dehydrated crystal==
<StructureSection load='3td6' size='340' side='right' caption='[[3td6]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='3td6' size='340' side='right'caption='[[3td6]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3td6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TD6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3td6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TD6 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tck|3tck]], [[3tcn|3tcn]], [[3td2|3td2]], [[2z2i|2z2i]], [[2z2j|2z2j]], [[2z2k|2z2k]], [[2pth|2pth]], [[2jrc|2jrc]], [[3p2j|3p2j]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT1042, MTCY10G2.35, pth, Rv1014c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3td6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3td6 OCA], [https://pdbe.org/3td6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3td6 RCSB], [https://www.ebi.ac.uk/pdbsum/3td6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3td6 ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aminoacyl-tRNA_hydrolase Aminoacyl-tRNA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.29 3.1.1.29] </span></td></tr>
</table>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3td6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3td6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3td6 RCSB], [http://www.ebi.ac.uk/pdbsum/3td6 PDBsum]</span></td></tr>
== Function ==
<table>
[https://www.uniprot.org/uniprot/PTH_MYCTU PTH_MYCTU] The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structures of new crystal forms of Mycobacterium tuberculosis peptidyl-tRNA hydrolase and functionally important plasticity of the molecule.,Selvaraj M, Ahmad R, Varshney U, Vijayan M Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt, 2):124-8. Epub 2012 Jan 21. PMID:22297982<ref>PMID:22297982</ref>
Structures of new crystal forms of Mycobacterium tuberculosis peptidyl-tRNA hydrolase and functionally important plasticity of the molecule.,Selvaraj M, Ahmad R, Varshney U, Vijayan M Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt, 2):124-8. Epub 2012 Jan 21. PMID:22297982<ref>PMID:22297982</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3td6" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aminoacyl-tRNA hydrolase]]
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Ahmad, R.]]
[[Category: Ahmad R]]
[[Category: Selvaraj, M.]]
[[Category: Selvaraj M]]
[[Category: Varshney, U.]]
[[Category: Varshney U]]
[[Category: Vijayan, M.]]
[[Category: Vijayan M]]
[[Category: Cytosol]]
[[Category: Hydrolase]]
[[Category: Hydrolysis of peptidyl-trna]]
[[Category: Peptidyl-trna]]
[[Category: Pth]]