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==HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second domain)==
==HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second domain)==
<StructureSection load='4emz' size='340' side='right' caption='[[4emz]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='4emz' size='340' side='right'caption='[[4emz]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4emz]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EMZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EMZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4emz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EMZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EMZ FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4en2|4en2]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4emz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4emz OCA], [https://pdbe.org/4emz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4emz RCSB], [https://www.ebi.ac.uk/pdbsum/4emz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4emz ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nef ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1]), HLA-2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), Ap1m1, Cltnm ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
</table>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4emz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4emz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4emz RCSB], [http://www.ebi.ac.uk/pdbsum/4emz PDBsum]</span></td></tr>
== Function ==
<table>
[[https://www.uniprot.org/uniprot/Q90VU7_9HIV1 Q90VU7_9HIV1]]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4emz" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Adaptin|Adaptin]]
*[[Adaptin 3D structures|Adaptin 3D structures]]
*[[Protein Nef|Protein Nef]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Jia, X.]]
[[Category: Jia X]]
[[Category: Xiong, Y.]]
[[Category: Xiong Y]]
[[Category: Adaptor protein complex 1]]
[[Category: Antigen presentation]]
[[Category: Clasp]]
[[Category: Hiv]]
[[Category: Host defense]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Membrane trafficking]]
[[Category: Mhc-i]]
[[Category: Mu1 adaptin subunit]]
[[Category: Nef]]
[[Category: Sorting motif recognition]]
[[Category: Viral hijacking]]
[[Category: Viral protein-immune system complex]]
Retrieved from "https://proteopedia.org/4emz"