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==CRYSTAL STRUCTURE OF RXLR EFFECTOR PEXRD2 FROM PHYTOPHTHORA INFESTANS==
 
<StructureSection load='3zrg' size='340' side='right' caption='[[3zrg]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
==Crystal structure of RxLR effector PexRD2 from Phytophthora infestans==
<StructureSection load='3zrg' size='340' side='right'caption='[[3zrg]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3zrg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Phytophthora_infestans Phytophthora infestans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZRG FirstGlance]. <br>
<table><tr><td colspan='2'>[[3zrg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Phytophthora_infestans Phytophthora infestans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZRG FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zr8|3zr8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zrg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zrg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zrg RCSB], [http://www.ebi.ac.uk/pdbsum/3zrg PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zrg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zrg OCA], [https://pdbe.org/3zrg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zrg RCSB], [https://www.ebi.ac.uk/pdbsum/3zrg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zrg ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RD2_PHYIT RD2_PHYIT] Effector that enhances P.infestans colonization of Nicotiana benthamiana leaves (PubMed:24632534, PubMed:30329083). Induces a weak Cell death response in N. benthamiana. PexRD2-induced cell death is dependent on SGT1, suggesting that PexRD2 is recognized by the plant immune system (PubMed:19794118). Interacts with the kinase domain of the host MAPKKK epsilon, a positive regulator of cell death associated with plant immunity, and perturbs signaling pathways triggered by MAPKKK epsilon (PubMed:24632534, PubMed:28386988).<ref>PMID:19794118</ref> <ref>PMID:24632534</ref> <ref>PMID:28386988</ref> <ref>PMID:30329083</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3zrg" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Phytophthora infestans]]
[[Category: Phytophthora infestans]]
[[Category: Banfield, M J.]]
[[Category: Banfield MJ]]
[[Category: Blumenschein, T M.A.]]
[[Category: Blumenschein TMA]]
[[Category: Boutemy, L S.]]
[[Category: Boutemy LS]]
[[Category: Clarke, T A.]]
[[Category: Clarke TA]]
[[Category: Hughes, R K.]]
[[Category: Hughes RK]]
[[Category: Kamoun, S.]]
[[Category: Kamoun S]]
[[Category: King, S R.F.]]
[[Category: King SRF]]
[[Category: Win, J.]]
[[Category: Win J]]
[[Category: Plant pathogen interaction]]
[[Category: Protein binding]]
Retrieved from "https://proteopedia.org/3zrg"