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==Vaccinia virus D8L IMV envelope protein in complex with Fab of murine IgG2a LA5==
==Vaccinia virus D8L IMV envelope protein in complex with Fab of murine IgG2a LA5==
<StructureSection load='4etq' size='340' side='right' caption='[[4etq]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='4etq' size='340' side='right'caption='[[4etq]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4etq]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ETQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ETQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4etq]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ETQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ETQ FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ebq|4ebq]], [[4e9o|4e9o]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IgG2a, IGHV1S127*01 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus]), IgG2a, IGKV4-55*01 germ line ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus]), D8L, VACAC2_124, VACCL3_124, VAC_DPP17_124 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4etq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4etq OCA], [https://pdbe.org/4etq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4etq RCSB], [https://www.ebi.ac.uk/pdbsum/4etq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4etq ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4etq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4etq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4etq RCSB], [http://www.ebi.ac.uk/pdbsum/4etq PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/Q1M1K6_9POXV Q1M1K6_9POXV]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4etq" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Monoclonal Antibody|Monoclonal Antibody]]
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Vaccinia virus]]
[[Category: Vaccinia virus]]
[[Category: Matho, M H.]]
[[Category: Matho MH]]
[[Category: Zajonc, D M.]]
[[Category: Zajonc DM]]
[[Category: Beta sheet]]
[[Category: Carbonic anhydrase fold]]
[[Category: Cdr]]
[[Category: Chondroitin-sulfate binding site]]
[[Category: Constant domain]]
[[Category: Delta 262]]
[[Category: Hypervariable region]]
[[Category: Igg domain]]
[[Category: Igg2a]]
[[Category: Immune system-viral protein complex]]
[[Category: Loose knot]]
[[Category: Neutralizing antibody]]
[[Category: Variable domain]]

Latest revision as of 02:51, 21 November 2024

Vaccinia virus D8L IMV envelope protein in complex with Fab of murine IgG2a LA5

4etq, resolution 2.10Å

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