4fgd: Difference between revisions
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==Structure of the effector protein Tse1 from Pseudomonas aeruginosa, selenomethionine variant== | ==Structure of the effector protein Tse1 from Pseudomonas aeruginosa, selenomethionine variant== | ||
<StructureSection load='4fgd' size='340' side='right' caption='[[4fgd]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='4fgd' size='340' side='right'caption='[[4fgd]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4fgd]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4fgd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FGD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FGD FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand= | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fgd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fgd OCA], [https://pdbe.org/4fgd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fgd RCSB], [https://www.ebi.ac.uk/pdbsum/4fgd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fgd ProSAT]</span></td></tr> | |||
<tr | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/TSE1_PSEAE TSE1_PSEAE] Toxin secreted by the H1 type VI (H1-T6SS) secretion system into the periplasm of recipient cells. Degrades peptidoglycan via amidase activity thereby helping itself to compete with other bacteria (PubMed:21776080, PubMed:22931054, PubMed:22813741, PubMed:22700987). To protect itself, the bacterium synthesizes immunity protein Tsi1 that specifically interacts with and inactivates cognate toxin (PubMed:21776080, PubMed:22931054, PubMed:22700987).<ref>PMID:21776080</ref> <ref>PMID:22700987</ref> <ref>PMID:22813741</ref> <ref>PMID:22931054</ref> | |||
<table> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4fgd" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Pseudomonas aeruginosa]] | [[Category: Large Structures]] | ||
[[Category: Barends | [[Category: Pseudomonas aeruginosa PAO1]] | ||
[[Category: Benz | [[Category: Barends TRM]] | ||
[[Category: Meinhart | [[Category: Benz J]] | ||
[[Category: Sendlmeier | [[Category: Meinhart A]] | ||
[[Category: Sendlmeier C]] | |||
