2q1e: Difference between revisions

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==Altered dimer interface decreases stability in an amyloidogenic kappa1 Bence Jones protein.==
==Altered dimer interface decreases stability in an amyloidogenic kappa1 Bence Jones protein.==
<StructureSection load='2q1e' size='340' side='right' caption='[[2q1e]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='2q1e' size='340' side='right'caption='[[2q1e]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2q1e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q1E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Q1E FirstGlance]. <br>
<table><tr><td colspan='2'>[[2q1e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q1E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q1E FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mutant of Vk1 O18/O8 germline ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q1e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q1e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2q1e RCSB], [http://www.ebi.ac.uk/pdbsum/2q1e PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q1e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q1e OCA], [https://pdbe.org/2q1e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q1e RCSB], [https://www.ebi.ac.uk/pdbsum/2q1e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q1e ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A2NI60_HUMAN A2NI60_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2q1e" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Baden, E M.]]
[[Category: Large Structures]]
[[Category: Ramirez-Alvarado, M.]]
[[Category: Baden EM]]
[[Category: Thompson, J R.]]
[[Category: Ramirez-Alvarado M]]
[[Category: Al]]
[[Category: Thompson JR]]
[[Category: Amyloid]]
[[Category: Immunoglobulin]]
[[Category: Light chain]]
[[Category: Light chain amyloidosis]]
[[Category: Light chain variable domain]]
[[Category: Protein fibril]]
Retrieved from "https://proteopedia.org/2q1e"