3wuz: Difference between revisions
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==Crystal structure of the Ig V-set domain of human paired immunoglobulin-like type 2 receptor alpha== | ==Crystal structure of the Ig V-set domain of human paired immunoglobulin-like type 2 receptor alpha== | ||
<StructureSection load='3wuz' size='340' side='right' caption='[[3wuz]], [[Resolution|resolution]] 1.30Å' scene=''> | <StructureSection load='3wuz' size='340' side='right'caption='[[3wuz]], [[Resolution|resolution]] 1.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3wuz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WUZ OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[3wuz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WUZ FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3Å</td></tr> | ||
<tr><td class="sblockLbl"><b>[[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wuz OCA], [https://pdbe.org/3wuz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wuz RCSB], [https://www.ebi.ac.uk/pdbsum/3wuz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wuz ProSAT]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PILRA_HUMAN PILRA_HUMAN] Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRA is thought to act as a cellular signaling inhibitory receptor by recruiting cytoplasmic phosphatases like PTPN6/SHP-1 and PTPN11/SHP-2 via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Receptor for PIANP.<ref>PMID:10903717</ref> <ref>PMID:18358807</ref> <ref>PMID:21241660</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Arase | [[Category: Homo sapiens]] | ||
[[Category: Kajikawa | [[Category: Large Structures]] | ||
[[Category: Kogure | [[Category: Arase H]] | ||
[[Category: Kuroki | [[Category: Kajikawa M]] | ||
[[Category: Maenaka | [[Category: Kogure A]] | ||
[[Category: Maita | [[Category: Kuroki K]] | ||
[[Category: Nakamura | [[Category: Maenaka K]] | ||
[[Category: Ose | [[Category: Maita N]] | ||
[[Category: Satoh | [[Category: Nakamura S]] | ||
[[Category: Tabata | [[Category: Ose T]] | ||
[[Category: Wang | [[Category: Satoh T]] | ||
[[Category: Yamaguchi | [[Category: Tabata S]] | ||
[[Category: Wang J]] | |||
[[Category: Yamaguchi M]] | |||
Latest revision as of 08:47, 20 March 2024
Crystal structure of the Ig V-set domain of human paired immunoglobulin-like type 2 receptor alpha
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