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==Crystal structure of Staphylcoccal nuclease variant Delta+PHS I72K V74K at cryogenic temperature==
==Crystal structure of Staphylcoccal nuclease variant Delta+PHS I72K V74K at cryogenic temperature==
<StructureSection load='4pmc' size='340' side='right' caption='[[4pmc]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='4pmc' size='340' side='right'caption='[[4pmc]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4pmc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PMC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PMC FirstGlance]. <br>
<table><tr><td colspan='2'>[[4pmc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PMC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PMC FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bdc|3bdc]], [[2rbm|2rbm]], [[3ruz|3ruz]], [[4pmb|4pmb]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pmc OCA], [https://pdbe.org/4pmc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pmc RCSB], [https://www.ebi.ac.uk/pdbsum/4pmc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pmc ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pmc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pmc RCSB], [http://www.ebi.ac.uk/pdbsum/4pmc PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
 
==See Also==
*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Micrococcal nuclease]]
[[Category: Large Structures]]
[[Category: Garcia-Moreno, E B.]]
[[Category: Staphylococcus aureus]]
[[Category: Schlessman, J L.]]
[[Category: Garcia-Moreno EB]]
[[Category: Sorenson, J L.]]
[[Category: Schlessman JL]]
[[Category: Hydrolase]]
[[Category: Sorenson JL]]
[[Category: Hyperstable]]
[[Category: Ionizable group]]
[[Category: Nuclease]]
[[Category: Pdtp]]
Retrieved from "https://proteopedia.org/4pmc"