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==Crystal structure of Mutant C221D of Carbapenemase CphA from Aeromonas Hydrophila==
==Crystal structure of Mutant C221D of Carbapenemase CphA from Aeromonas Hydrophila==
<StructureSection load='3t9m' size='340' side='right' caption='[[3t9m]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
<StructureSection load='3t9m' size='340' side='right'caption='[[3t9m]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3t9m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeromonas_hydrophila Aeromonas hydrophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T9M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T9M FirstGlance]. <br>
<table><tr><td colspan='2'>[[3t9m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeromonas_hydrophila Aeromonas hydrophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T9M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T9M FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x8g|1x8g]], [[1x8h|1x8h]], [[3sw3|3sw3]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cphA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=644 Aeromonas hydrophila])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t9m OCA], [https://pdbe.org/3t9m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t9m RCSB], [https://www.ebi.ac.uk/pdbsum/3t9m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t9m ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
</table>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t9m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t9m RCSB], [http://www.ebi.ac.uk/pdbsum/3t9m PDBsum]</span></td></tr>
== Function ==
<table>
[https://www.uniprot.org/uniprot/BLAB_AERHY BLAB_AERHY] Can hydrolyze carbapenem compounds.


==See Also==
==See Also==
*[[Beta-lactamase|Beta-lactamase]]
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aeromonas hydrophila]]
[[Category: Aeromonas hydrophila]]
[[Category: Beta-lactamase]]
[[Category: Large Structures]]
[[Category: Delbruck, H.]]
[[Category: Delbruck H]]
[[Category: Hoffmann, K M.V.]]
[[Category: Hoffmann KMV]]
[[Category: Hydrolase]]

Latest revision as of 13:21, 14 March 2024

Crystal structure of Mutant C221D of Carbapenemase CphA from Aeromonas Hydrophila

3t9m, resolution 2.03Å

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