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==Crystal Structure of Leishmania major dihydroorotate dehydrogenase mutant D171A==
==Crystal Structure of Leishmania major dihydroorotate dehydrogenase mutant D171A==
<StructureSection load='3tro' size='340' side='right' caption='[[3tro]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
<StructureSection load='3tro' size='340' side='right'caption='[[3tro]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3tro]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TRO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TRO FirstGlance]. <br>
<table><tr><td colspan='2'>[[3tro]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major_strain_Friedlin Leishmania major strain Friedlin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TRO FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gye|3gye]], [[3gz3|3gz3]], [[3mjy|3mjy]], [[3mhu|3mhu]], [[3snq|3snq]], [[3snu|3snu]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DHODH, lmjf16.0530, LMJF_16_0530 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5664 Leishmania major])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tro OCA], [https://pdbe.org/3tro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tro RCSB], [https://www.ebi.ac.uk/pdbsum/3tro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tro ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase Dihydroorotate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.1 1.3.3.1] </span></td></tr>
</table>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tro OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tro RCSB], [http://www.ebi.ac.uk/pdbsum/3tro PDBsum]</span></td></tr>
== Function ==
<table>
[https://www.uniprot.org/uniprot/Q4QEW7_LEIMA Q4QEW7_LEIMA]


==See Also==
==See Also==
*[[Dihydroorotate dehydrogenase|Dihydroorotate dehydrogenase]]
*[[Dihydroorotate dehydrogenase 3D structures|Dihydroorotate dehydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Dihydroorotate oxidase]]
[[Category: Large Structures]]
[[Category: Leishmania major]]
[[Category: Leishmania major strain Friedlin]]
[[Category: Nonato, M C.]]
[[Category: Nonato MC]]
[[Category: Pinheiro, M P.]]
[[Category: Pinheiro MP]]
[[Category: Souza, A L.de.]]
[[Category: De Souza AL]]
[[Category: Dhodh]]
[[Category: Lmdhodh]]
[[Category: Oxidoreductase]]
[[Category: Pyrd]]

Latest revision as of 13:37, 14 March 2024

Crystal Structure of Leishmania major dihydroorotate dehydrogenase mutant D171A

3tro, resolution 1.86Å

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