4qmi: Difference between revisions
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The | ==The XMAP215 family drives microtubule polymerization using a structurally diverse TOG array== | ||
<StructureSection load='4qmi' size='340' side='right'caption='[[4qmi]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4qmi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QMI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QMI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qmi OCA], [https://pdbe.org/4qmi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qmi RCSB], [https://www.ebi.ac.uk/pdbsum/4qmi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qmi ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CKAP5_HUMAN CKAP5_HUMAN] Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles.<ref>PMID:12569123</ref> <ref>PMID:21646404</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Currie JD]] | |||
[[Category: Fox JC]] | |||
[[Category: Howard AE]] | |||
[[Category: Rogers SL]] | |||
[[Category: Slep KC]] | |||
Latest revision as of 12:47, 1 March 2024
The XMAP215 family drives microtubule polymerization using a structurally diverse TOG array
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