4qoh: Difference between revisions
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New page: '''Unreleased structure''' The entry 4qoh is ON HOLD until Paper Publication Authors: Serriere, J., Boutin, J.A., Isabet, T., Antoine, M., Ferry, G. Description: Crystal structure of f... |
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==Crystal structure of fad quinone reductase 2 in complex with resveratrol at 1.6A== | |||
<StructureSection load='4qoh' size='340' side='right'caption='[[4qoh]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4qoh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QOH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QOH FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=STL:RESVERATROL'>STL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qoh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qoh OCA], [https://pdbe.org/4qoh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qoh RCSB], [https://www.ebi.ac.uk/pdbsum/4qoh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qoh ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref> | |||
==See Also== | |||
*[[Quinone reductase|Quinone reductase]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Antoine M]] | |||
[[Category: Boutin JA]] | |||
[[Category: Ferry G]] | |||
[[Category: Isabet T]] | |||
[[Category: Serriere J]] | |||
