4qpn: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "4qpn" [edit=sysop:move=sysop] |
No edit summary |
||
| (5 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal Structure of Human Methyltransferase-Like Protein 21B== | |||
<StructureSection load='4qpn' size='340' side='right'caption='[[4qpn]], [[Resolution|resolution]] 1.25Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4qpn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QPN FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qpn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qpn OCA], [https://pdbe.org/4qpn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qpn RCSB], [https://www.ebi.ac.uk/pdbsum/4qpn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qpn ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/EFMT3_HUMAN EFMT3_HUMAN] Protein-lysine methyltransferase that selectively mono-, di- and trimethylates 'Lys-165' of the translation elongation factors EEF1A1 and EEF1A2 in an aminoacyl-tRNA and GTP-dependent manner. EEF1A1 methylation by EEF1AKMT3 is dynamic as well as inducible by stress conditions, such as ER-stress, and plays a regulatory role on mRNA translation.<ref>PMID:28108655</ref> <ref>PMID:28663172</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Brown PJ]] | |||
[[Category: Edwards AM]] | |||
[[Category: Graslund S]] | |||
[[Category: He H]] | |||
[[Category: Hong BS]] | |||
[[Category: Li Y]] | |||
[[Category: Seitova A]] | |||
[[Category: Tempel W]] | |||
Latest revision as of 17:35, 20 September 2023
Crystal Structure of Human Methyltransferase-Like Protein 21B
| ||||||||||||
