2mp2: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
(6 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Solution structure of SUMO dimer in complex with SIM2-3 from RNF4==
==Solution structure of SUMO dimer in complex with SIM2-3 from RNF4==
<StructureSection load='2mp2' size='340' side='right' caption='[[2mp2]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2mp2' size='340' side='right'caption='[[2mp2]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2mp2]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MP2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2mp2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MP2 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mp2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mp2 RCSB], [http://www.ebi.ac.uk/pdbsum/2mp2 PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<table>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mp2 OCA], [https://pdbe.org/2mp2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mp2 RCSB], [https://www.ebi.ac.uk/pdbsum/2mp2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mp2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SUMO3_HUMAN SUMO3_HUMAN] Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.<ref>PMID:11451954</ref> <ref>PMID:18538659</ref>
 
==See Also==
*[[SUMO 3D Structures|SUMO 3D Structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hay, R T.]]
[[Category: Homo sapiens]]
[[Category: Leidecker, O.]]
[[Category: Large Structures]]
[[Category: Marchant, J.]]
[[Category: Mus musculus]]
[[Category: Matthews, S J.]]
[[Category: Hay RT]]
[[Category: Plechanovov, A.]]
[[Category: Leidecker O]]
[[Category: Sebastian, K.]]
[[Category: Marchant J]]
[[Category: Simpson, P.]]
[[Category: Matthews SJ]]
[[Category: Xu, Y.]]
[[Category: Plechanovov A]]
[[Category: Complex]]
[[Category: Sebastian K]]
[[Category: Dimer]]
[[Category: Simpson P]]
[[Category: Protein binding]]
[[Category: Xu Y]]
[[Category: Rnf4]]
[[Category: Sim]]
[[Category: Sumo]]
Retrieved from "https://proteopedia.org/2mp2"