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==Constructing tailored isoprenoid products by structure-guided modification of geranylgeranyl reductase==
==Constructing tailored isoprenoid products by structure-guided modification of geranylgeranyl reductase==
<StructureSection load='4opu' size='340' side='right' caption='[[4opu]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='4opu' size='340' side='right'caption='[[4opu]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4opu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OPU FirstGlance]. <br>
<table><tr><td colspan='2'>[[4opu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfolobus_acidocaldarius_DSM_639 Sulfolobus acidocaldarius DSM 639]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OPU FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FDA:DIHYDROFLAVINE-ADENINE+DINUCLEOTIDE'>FDA</scene>, <scene name='pdbligand=GRG:GERANYLGERANYL+DIPHOSPHATE'>GRG</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4opc|4opc]], [[4opd|4opd]], [[4opg|4opg]], [[4opi|4opi]], [[4opl|4opl]], [[4opt|4opt]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FDA:DIHYDROFLAVINE-ADENINE+DINUCLEOTIDE'>FDA</scene>, <scene name='pdbligand=GRG:GERANYLGERANYL+DIPHOSPHATE'>GRG</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Geranylgeranyl_diphosphate_reductase Geranylgeranyl diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.83 1.3.1.83] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4opu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4opu OCA], [https://pdbe.org/4opu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4opu RCSB], [https://www.ebi.ac.uk/pdbsum/4opu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4opu ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4opu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4opu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4opu RCSB], [http://www.ebi.ac.uk/pdbsum/4opu PDBsum]</span></td></tr>
</table>
<table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4opu" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Geranylgeranyl diphosphate reductase]]
[[Category: Large Structures]]
[[Category: Adams, P D.]]
[[Category: Sulfolobus acidocaldarius DSM 639]]
[[Category: Keasling, J D.]]
[[Category: Adams PD]]
[[Category: Kung, Y.]]
[[Category: Keasling JD]]
[[Category: Liu, C.]]
[[Category: Kung Y]]
[[Category: McAndrew, R P.]]
[[Category: Liu C]]
[[Category: Pereira, J H.]]
[[Category: McAndrew RP]]
[[Category: Xie, X.]]
[[Category: Pereira JH]]
[[Category: Archaeal protein]]
[[Category: Xie X]]
[[Category: Oxidoreductase]]
[[Category: Rossmann fold]]

Latest revision as of 03:23, 21 November 2024

Constructing tailored isoprenoid products by structure-guided modification of geranylgeranyl reductase

4opu, resolution 2.70Å

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