2mq6: Difference between revisions

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'''Unreleased structure'''


The entry 2mq6 is ON HOLD  until Paper Publication
==Solution structure of Y125F mutant of eRF1 N-domain==
 
<StructureSection load='2mq6' size='340' side='right'caption='[[2mq6]]' scene=''>
Authors: Pillay, S., Li, Y., Wong, L., Pervushin, K.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2mq6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MQ6 FirstGlance]. <br>
Description: Solution structure of Y125F mutant of eRF1 N-domain
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mq6 OCA], [https://pdbe.org/2mq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mq6 RCSB], [https://www.ebi.ac.uk/pdbsum/2mq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mq6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ERF1_HUMAN ERF1_HUMAN] Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.<ref>PMID:7990965</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Li Y]]
[[Category: Pervushin K]]
[[Category: Pillay S]]
[[Category: Wong L]]