4pg3: Difference between revisions

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==Crystal structure of KRS complexed with inhibitor==
==Crystal structure of KRS complexed with inhibitor==
<StructureSection load='4pg3' size='340' side='right' caption='[[4pg3]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='4pg3' size='340' side='right'caption='[[4pg3]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4pg3]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PG3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PG3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4pg3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PG3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PG3 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KRS:(3R)-3-[[(2R,6S)-6-METHYLOXAN-2-YL]METHYL]-6,8-BIS(OXIDANYL)-3,4-DIHYDROISOCHROMEN-1-ONE'>KRS</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.696&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysine--tRNA_ligase Lysine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.6 6.1.1.6] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KRS:CLADOSPORIN'>KRS</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pg3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pg3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pg3 RCSB], [http://www.ebi.ac.uk/pdbsum/4pg3 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pg3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pg3 OCA], [https://pdbe.org/4pg3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pg3 RCSB], [https://www.ebi.ac.uk/pdbsum/4pg3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pg3 ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8IDJ8_PLAF7 Q8IDJ8_PLAF7]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4pg3" style="background-color:#fffaf0;"></div>
==See Also==
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lysine--tRNA ligase]]
[[Category: Large Structures]]
[[Category: Belrhali, H.]]
[[Category: Plasmodium falciparum 3D7]]
[[Category: Khan, S.]]
[[Category: Belrhali H]]
[[Category: Sharma, A.]]
[[Category: Khan S]]
[[Category: Yogavel, M.]]
[[Category: Sharma A]]
[[Category: Complex]]
[[Category: Yogavel M]]
[[Category: Inhibitor]]
[[Category: Kr]]
[[Category: Ligase-ligase inhibitor complex]]

Latest revision as of 07:16, 27 September 2023

Crystal structure of KRS complexed with inhibitor

4pg3, resolution 2.70Å

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