4quv: Difference between revisions
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New page: '''Unreleased structure''' The entry 4quv is ON HOLD until Paper Publication Authors: Li, X., Blobel, G. Description: |
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==Structure of an integral membrane delta(14)-sterol reductase== | |||
<StructureSection load='4quv' size='340' side='right'caption='[[4quv]], [[Resolution|resolution]] 2.74Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4quv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylotuvimicrobium_alcaliphilum_20Z Methylotuvimicrobium alcaliphilum 20Z]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QUV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QUV FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.743Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4quv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4quv OCA], [https://pdbe.org/4quv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4quv RCSB], [https://www.ebi.ac.uk/pdbsum/4quv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4quv ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ERG_META2 ERG_META2] Reduces the C14=C15 double bond of 4,4-dimethyl-cholesta-8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol. Complements the deletion of the Delta(14)-sterol reductase gene ERG24 in yeast.<ref>PMID:25307054</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Methylotuvimicrobium alcaliphilum 20Z]] | |||
[[Category: Blobel G]] | |||
[[Category: Li X]] | |||
Latest revision as of 12:48, 1 March 2024
Structure of an integral membrane delta(14)-sterol reductase
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