4u4p: Difference between revisions
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New page: '''Unreleased structure''' The entry 4u4p is ON HOLD Authors: Uchiyama, S., Kawahara, K., Hosokawa, Y., Fukakusa, S., Nakamura, S., Noda, M., Takino, R., Miyahara, Y., Maruno, T., Kobay... |
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==Crystal structure of the human condensin SMC hinge domain heterodimer with short coiled coils== | |||
<StructureSection load='4u4p' size='340' side='right'caption='[[4u4p]], [[Resolution|resolution]] 1.89Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4u4p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U4P FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u4p OCA], [https://pdbe.org/4u4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u4p RCSB], [https://www.ebi.ac.uk/pdbsum/4u4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u4p ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SMC2_HUMAN SMC2_HUMAN] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.<ref>PMID:11136719</ref> | |||
==See Also== | |||
*[[Condensin|Condensin]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Fukakusa S]] | |||
[[Category: Fukui K]] | |||
[[Category: Hosokawa Y]] | |||
[[Category: Kawahara K]] | |||
[[Category: Kobayashi Y]] | |||
[[Category: Maruno T]] | |||
[[Category: Miyahara Y]] | |||
[[Category: Nakamura S]] | |||
[[Category: Noda M]] | |||
[[Category: Ohkubo T]] | |||
[[Category: Oki H]] | |||
[[Category: Takino R]] | |||
[[Category: Uchiyama S]] | |||
