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[[Image:1d96.gif|left|200px]]


{{Structure
==MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA==
|PDB= 1d96 |SIZE=350|CAPTION= <scene name='initialview01'>1d96</scene>, resolution 2.000&Aring;
<StructureSection load='1d96' size='340' side='right'caption='[[1d96]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE=
== Structural highlights ==
|LIGAND=
<table><tr><td colspan='2'>[[1d96]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D96 FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d96 OCA], [https://pdbe.org/1d96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d96 RCSB], [https://www.ebi.ac.uk/pdbsum/1d96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d96 ProSAT]</span></td></tr>
}}
</table>
 
__TOC__
'''MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA'''
</StructureSection>
 
[[Category: Large Structures]]
 
[[Category: Fujii S]]
==Overview==
[[Category: Rich A]]
The molecule r(GCG)d(TATACGC) is self-complementary and forms two DNA--RNA hybrid segments surrounding a central region of double helical DNA; its molecular structure has been solved by X-ray analysis. All three parts of the molecule adopt a conformation which is close to that seen in the 11-fold RNA double helix. The conformation of the ribonucleotides is partly determined by water molecules bridging between the ribose O2' hydroxyl group and cytosine O2. The hybrid-DNA duplex junction contains no structural discontinuities. However, the central DNA TATA sequence has some structural irregularities.
[[Category: Van Boeckel SAA]]
 
[[Category: Van Boom JH]]
==About this Structure==
[[Category: Van Der Marel GA]]
1D96 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D96 OCA].  
[[Category: Wang AH-J]]
 
==Reference==
Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA., Wang AH, Fujii S, van Boom JH, van der Marel GA, van Boeckel SA, Rich A, Nature. 1982 Oct 14;299(5884):601-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/6181416 6181416]
[[Category: Protein complex]]
[[Category: Boeckel, S A.A Van.]]
[[Category: Boom, J H.Van.]]
[[Category: Fujii, S.]]
[[Category: Marel, G A.Van Der.]]
[[Category: Rich, A.]]
[[Category: Wang, A H.J.]]
[[Category: a-dna/rna]]
[[Category: double helix]]
 
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