4qwe: Difference between revisions

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'''Unreleased structure'''


The entry 4qwe is ON HOLD  until Aug 28 2015
==TERNARY CRYSTAL STRUCTURES of A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH DNA AND (-)FTC-DP==
<StructureSection load='4qwe' size='340' side='right'caption='[[4qwe]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4qwe]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QWE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FTD:[(2R,5S)-5-(4-AMINO-5-FLUORO-2-OXO-3,6-DIHYDROPYRIMIDIN-1(2H)-YL)-1,3-OXATHIOLAN-2-YL]METHYL+TRIHYDROGEN+DIPHOSPHATE'>FTD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qwe OCA], [https://pdbe.org/4qwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qwe RCSB], [https://www.ebi.ac.uk/pdbsum/4qwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qwe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPO4_SACS2 DPO4_SACS2] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.


Authors: Gaur, V., Suo, Z.
==See Also==
 
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
Description: TERNARY CRYSTAL STRUCTURES of A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH DNA AND (-)FTC-DP
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharolobus solfataricus P2]]
[[Category: Gaur V]]
[[Category: Suo Z]]