4q1p: Difference between revisions

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'''Unreleased structure'''


The entry 4q1p is ON HOLD  until Paper Publication
==Galectin-1 in Complex with Ligand NB169==
<StructureSection load='4q1p' size='340' side='right'caption='[[4q1p]], [[Resolution|resolution]] 1.46&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4q1p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q1P FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.46&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2XT:PROPYL+2-(ACETYLAMINO)-4-O-{3-O-[(1-BENZYL-1H-1,2,3-TRIAZOL-4-YL)METHYL]-BETA-D-GALACTOPYRANOSYL}-2-DEOXY-BETA-D-GLUCOPYRANOSIDE'>2XT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q1p OCA], [https://pdbe.org/4q1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q1p RCSB], [https://www.ebi.ac.uk/pdbsum/4q1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q1p ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref>


Authors: Grimm, C., Bertleff-Zieschang, N.
==See Also==
 
*[[Galectin 3D structures|Galectin 3D structures]]
Description: Galectin-1 in Complex with Ligand NB169
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bertleff-Zieschang N]]
[[Category: Grimm C]]
Retrieved from "https://proteopedia.org/4q1p"