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'''Unreleased structure'''


The entry 4u9m is ON HOLD
==Structure of the DNA duplex d(ATTAAT)2 with Hoogsteen hydrogen bonds==
<StructureSection load='4u9m' size='340' side='right'caption='[[4u9m]], [[Resolution|resolution]] 3.13&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4u9m]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U9M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U9M FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.13&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u9m OCA], [https://pdbe.org/4u9m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u9m RCSB], [https://www.ebi.ac.uk/pdbsum/4u9m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u9m ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The traditional Watson-Crick base pairs in DNA may occasionally adopt a Hoogsteen conformation, with a different organization of hydrogen bonds. Previous crystal structures have shown that the Hoogsteen conformation is favored in alternating AT sequences of DNA. Here we present new data for a different sequence, d(ATTAAT)2, which is also found in the Hoogsteen conformation. Thus we demonstrate that other all-AT sequences of DNA with a different sequence may be found in the Hoogsteen conformation. We conclude that any all-AT sequence might acquire this conformation under appropriate conditions. We also compare the detailed features of DNA in either the Hoogsteen or Watson-Crick conformations.


Authors: Acosta-Reyes, F.J., Alechaga, E., Subirana, J.A., Campos, J.L.
Structure of the DNA Duplex d(ATTAAT)2 with Hoogsteen Hydrogen Bonds.,Acosta-Reyes FJ, Alechaga E, Subirana JA, Campos JL PLoS One. 2015 Mar 17;10(3):e0120241. doi: 10.1371/journal.pone.0120241., eCollection 2015. PMID:25781995<ref>PMID:25781995</ref>


Description: Structure of the DNA duplex d(ATTAAT)2 with Hoogsteen hydrogen bonds
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 4u9m" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Acosta-Reyes FJ]]
[[Category: Alechaga E]]
[[Category: Campos JL]]
[[Category: Subirana JA]]
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