1dxi: Difference between revisions

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[[Image:1dxi.gif|left|200px]]


{{Structure
==STRUCTURE DETERMINATION OF GLUCOSE ISOMERASE FROM STREPTOMYCES MURINUS AT 2.6 ANGSTROMS RESOLUTION==
|PDB= 1dxi |SIZE=350|CAPTION= <scene name='initialview01'>1dxi</scene>, resolution 2.6&Aring;
<StructureSection load='1dxi' size='340' side='right'caption='[[1dxi]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene>
<table><tr><td colspan='2'>[[1dxi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_murinus Streptomyces murinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DXI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DXI FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Xylose_isomerase Xylose isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.5 5.3.1.5]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dxi OCA], [https://pdbe.org/1dxi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dxi RCSB], [https://www.ebi.ac.uk/pdbsum/1dxi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dxi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/XYLA_STRMR XYLA_STRMR] Involved in D-xylose catabolism.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dx/1dxi_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dxi ConSurf].
<div style="clear:both"></div>


'''STRUCTURE DETERMINATION OF GLUCOSE ISOMERASE FROM STREPTOMYCES MURINUS AT 2.6 ANGSTROMS RESOLUTION'''
==See Also==
 
*[[D-xylose isomerase 3D structures|D-xylose isomerase 3D structures]]
 
__TOC__
==Overview==
</StructureSection>
Glucose isomerase from Streptomyces murinus has been crystallized in space group P4(1)2(1)2, cell dimensions a = b = 137.65 and c = 132.20 A. One dimer of the tetrametric molecule is found per asymmetric unit. An initial structure solution was obtained by the molecular replacement method. The crystallographic refinement was performed using molecular dynamics techniques with X-ray restraints. The final crystallographic R value is 21.4% at 2.6 A resolution including 3023 non-H atoms, two metal ions and two water molecules per monomer.
[[Category: Large Structures]]
 
==About this Structure==
1DXI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_murinus Streptomyces murinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DXI OCA].
 
==Reference==
Structure determination of glucose isomerase from Streptomyces murinus at 2.6 A resolution., Rasmussen H, la Cour T, Nyborg J, Schulein M, Acta Crystallogr D Biol Crystallogr. 1994 Mar 1;50(Pt 2):124-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15299450 15299450]
[[Category: Single protein]]
[[Category: Streptomyces murinus]]
[[Category: Streptomyces murinus]]
[[Category: Xylose isomerase]]
[[Category: La Cour T]]
[[Category: Cour, T La.]]
[[Category: Nyborg J]]
[[Category: Nyborg, J.]]
[[Category: Rasmussen H]]
[[Category: Rasmussen, H.]]
[[Category: Schulein M]]
[[Category: Schulein, M.]]
[[Category: MG]]
[[Category: isomerase(intramolecular oxidoreductase)]]
 
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