4r89: Difference between revisions

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'''Unreleased structure'''


The entry 4r89 is ON HOLD
==Crystal structure of paFAN1 - 5' flap DNA complex with Manganase==
 
<StructureSection load='4r89' size='340' side='right'caption='[[4r89]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
Authors: Cho, Y., Gwon, G.H., Kim, Y.R.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4r89]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R89 FirstGlance]. <br>
Description: nuclease_metal
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.002&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r89 OCA], [https://pdbe.org/4r89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r89 RCSB], [https://www.ebi.ac.uk/pdbsum/4r89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r89 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FAN1_PSEAE FAN1_PSEAE] Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Also has endonuclease activity toward 5'-flaps (PubMed:25319828).[UniProtKB:Q9Y2M0]<ref>PMID:24981866</ref> <ref>PMID:25319828</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Cho Y]]
[[Category: Gwon GH]]
[[Category: Kim YR]]
Retrieved from "https://proteopedia.org/4r89"