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==Crystal structure of ancestral apicomplexan lactate dehydrogenase with lactate.==
==Crystal structure of ancestral apicomplexan lactate dehydrogenase with lactate.==
<StructureSection load='4plf' size='340' side='right' caption='[[4plf]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
<StructureSection load='4plf' size='340' side='right'caption='[[4plf]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4plf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PLF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PLF FirstGlance]. <br>
<table><tr><td colspan='2'>[[4plf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Apicomplexa Apicomplexa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PLF FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4plc|4plc]], [[4plg|4plg]], [[4plh|4plh]], [[4plt|4plt]], [[4plv|4plv]], [[4plw|4plw]], [[4ply|4ply]], [[4plz|4plz]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4plf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4plf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4plf RCSB], [http://www.ebi.ac.uk/pdbsum/4plf PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4plf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4plf OCA], [https://pdbe.org/4plf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4plf RCSB], [https://www.ebi.ac.uk/pdbsum/4plf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4plf ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A075B5G8_9APIC A0A075B5G8_9APIC]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4plf" style="background-color:#fffaf0;"></div>
==See Also==
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Beckett, B C.]]
[[Category: Boucher, J I.]]
[[Category: Classen, S.]]
[[Category: Jacobowitz, J R.]]
[[Category: Theobald, D L.]]
[[Category: Ancestral sequence reconstruction]]
[[Category: Apicomplexa]]
[[Category: Apicomplexa]]
[[Category: Dehydrogenase]]
[[Category: Large Structures]]
[[Category: Oxidoreductase]]
[[Category: Beckett BC]]
[[Category: Specificity]]
[[Category: Boucher JI]]
[[Category: Classen S]]
[[Category: Jacobowitz JR]]
[[Category: Theobald DL]]

Latest revision as of 07:17, 27 September 2023

Crystal structure of ancestral apicomplexan lactate dehydrogenase with lactate.

4plf, resolution 1.35Å

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