1m7l: Difference between revisions

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==Solution Structure of the Coiled-Coil Trimerization Domain from Lung Surfactant Protein D==
==Solution Structure of the Coiled-Coil Trimerization Domain from Lung Surfactant Protein D==
<StructureSection load='1m7l' size='340' side='right' caption='[[1m7l]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''>
<StructureSection load='1m7l' size='340' side='right'caption='[[1m7l]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1m7l]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M7L FirstGlance]. <br>
<table><tr><td colspan='2'>[[1m7l]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M7L FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m7l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m7l RCSB], [http://www.ebi.ac.uk/pdbsum/1m7l PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<table>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m7l OCA], [https://pdbe.org/1m7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m7l RCSB], [https://www.ebi.ac.uk/pdbsum/1m7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m7l ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SFTPD_HUMAN SFTPD_HUMAN] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m7/1m7l_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m7/1m7l_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m7l ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1m7l" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Campbell, I D.]]
[[Category: Large Structures]]
[[Category: Comfort, D.]]
[[Category: Campbell ID]]
[[Category: Donoghue, S I.O.]]
[[Category: Comfort D]]
[[Category: Hoppe, H J.]]
[[Category: Hoppe H-J]]
[[Category: Kovacs, H.]]
[[Category: Kovacs H]]
[[Category: Nilges, M.]]
[[Category: Nilges M]]
[[Category: Reid, K B.M.]]
[[Category: O'Donoghue SI]]
[[Category: Ambiguous distance restraint]]
[[Category: Reid KBM]]
[[Category: Lung surfactant protein]]
[[Category: Nmr-spectroscopy]]
[[Category: Sugar binding protein]]
[[Category: Trimer]]
Retrieved from "https://proteopedia.org/1m7l"