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==Crystal Structure of scFv against peptide GCN4==
==Crystal Structure of scFv against peptide GCN4==
<StructureSection load='1p4i' size='340' side='right' caption='[[1p4i]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1p4i' size='340' side='right'caption='[[1p4i]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1p4i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P4I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P4I FirstGlance]. <br>
<table><tr><td colspan='2'>[[1p4i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P4I FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1p4b|1p4b]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p4i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p4i RCSB], [http://www.ebi.ac.uk/pdbsum/1p4i PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p4i OCA], [https://pdbe.org/1p4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p4i RCSB], [https://www.ebi.ac.uk/pdbsum/1p4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p4i ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LV1A_MOUSE LV1A_MOUSE]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p4/1p4i_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p4/1p4i_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p4i ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1p4i" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Monoclonal Antibody|Monoclonal Antibody]]
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Amstutz, P.]]
[[Category: Amstutz P]]
[[Category: Cambillau, C.]]
[[Category: Cambillau C]]
[[Category: Jermutus, L.]]
[[Category: Jermutus L]]
[[Category: Luginbuhl, B.]]
[[Category: Luginbuhl B]]
[[Category: Pluckthun, A.]]
[[Category: Pluckthun A]]
[[Category: Spinelli, S.]]
[[Category: Spinelli S]]
[[Category: Zahnd, C.]]
[[Category: Zahnd C]]
[[Category: Immune system]]
[[Category: Peptide binder]]
[[Category: Picomolar binder]]
[[Category: Scfv]]

Latest revision as of 07:23, 9 October 2024

Crystal Structure of scFv against peptide GCN4

1p4i, resolution 2.80Å

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