1txp: Difference between revisions

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==Heterogeneous Nuclear Ribonucleoprotein (hnRNP) C Oligomerization Domain Tetramer==
==Heterogeneous Nuclear Ribonucleoprotein (hnRNP) C Oligomerization Domain Tetramer==
<StructureSection load='1txp' size='340' side='right' caption='[[1txp]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1txp' size='340' side='right'caption='[[1txp]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1txp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TXP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TXP FirstGlance]. <br>
<table><tr><td colspan='2'>[[1txp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TXP FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HnRNP C1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1txp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1txp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1txp RCSB], [http://www.ebi.ac.uk/pdbsum/1txp PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1txp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1txp OCA], [https://pdbe.org/1txp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1txp RCSB], [https://www.ebi.ac.uk/pdbsum/1txp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1txp ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HNRPC_HUMAN HNRPC_HUMAN] Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.<ref>PMID:8264621</ref> <ref>PMID:7567451</ref> <ref>PMID:12509468</ref> <ref>PMID:16010978</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1txp" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Nucleoprotein|Nucleoprotein]]
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Krezel, A M.]]
[[Category: Large Structures]]
[[Category: Lestourgeon, W M.]]
[[Category: Krezel AM]]
[[Category: Whitson, S R.]]
[[Category: Lestourgeon WM]]
[[Category: Antiparallel four helix coiled coil tetramer hnrnpc]]
[[Category: Whitson SR]]
[[Category: Signaling protein]]
Retrieved from "https://proteopedia.org/1txp"