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==THE CRYSTAL STRUCTURE OF IRON SUPEROXIDE DISMUTASE FROM ALIIVIBRIO SALMONICIDA.==
 
<StructureSection load='2w7w' size='340' side='right' caption='[[2w7w]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
==The crystal structure of iron superoxide dismutase from Aliivibrio salmonicida.==
<StructureSection load='2w7w' size='340' side='right'caption='[[2w7w]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2w7w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aliivibrio_salmonicida Aliivibrio salmonicida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W7W FirstGlance]. <br>
<table><tr><td colspan='2'>[[2w7w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aliivibrio_salmonicida_LFI1238 Aliivibrio salmonicida LFI1238]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W7W FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w7w RCSB], [http://www.ebi.ac.uk/pdbsum/2w7w PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7w OCA], [https://pdbe.org/2w7w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w7w RCSB], [https://www.ebi.ac.uk/pdbsum/2w7w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w7w ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B6ENP9_ALISL B6ENP9_ALISL] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w7/2w7w_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w7/2w7w_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w7w ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2w7w" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Superoxide Dismutase|Superoxide Dismutase]]
*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aliivibrio salmonicida]]
[[Category: Aliivibrio salmonicida LFI1238]]
[[Category: Superoxide dismutase]]
[[Category: Large Structures]]
[[Category: Leiros, I.]]
[[Category: Leiros I]]
[[Category: Pedersen, H L.]]
[[Category: Pedersen HL]]
[[Category: Willassen, N P.]]
[[Category: Willassen NP]]
[[Category: Aliivibrio salmonicida]]
[[Category: Cold adaptation]]
[[Category: Differential scanning calorimetry]]
[[Category: Dsc]]
[[Category: Fesod]]
[[Category: Oxidoreductase]]
[[Category: Sodb]]
[[Category: Structural analysis]]
[[Category: Superoxide dismutase]]