2rcy: Difference between revisions
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==Crystal structure of Plasmodium falciparum pyrroline carboxylate reductase (MAL13P1.284) with NADP bound== | ==Crystal structure of Plasmodium falciparum pyrroline carboxylate reductase (MAL13P1.284) with NADP bound== | ||
<StructureSection load='2rcy' size='340' side='right' caption='[[2rcy]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='2rcy' size='340' side='right'caption='[[2rcy]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2rcy]] is a 5 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2rcy]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RCY FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rcy OCA], [https://pdbe.org/2rcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rcy RCSB], [https://www.ebi.ac.uk/pdbsum/2rcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rcy ProSAT]</span></td></tr> | |||
</table> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | == Function == | ||
<table> | [https://www.uniprot.org/uniprot/Q8IDC6_PLAF7 Q8IDC6_PLAF7] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rc/2rcy_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rc/2rcy_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rcy ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| Line 24: | Line 25: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Plasmodium falciparum 3D7]] | ||
[[Category: Amani | [[Category: Amani M]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Artz | [[Category: Artz JD]] | ||
[[Category: Bochkarev | [[Category: Bochkarev A]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Hassanali | [[Category: Hassanali A]] | ||
[[Category: Hui | [[Category: Hui R]] | ||
[[Category: Khuu | [[Category: Khuu C]] | ||
[[Category: Kozieradzki | [[Category: Kozieradzki I]] | ||
[[Category: Lew | [[Category: Lew J]] | ||
[[Category: Lin | [[Category: Lin YH]] | ||
[[Category: Ren | [[Category: Ren H]] | ||
[[Category: Schapira M]] | |||
[[Category: Schapira | [[Category: Sun X]] | ||
[[Category: Sun | [[Category: Sundstrom M]] | ||
[[Category: Sundstrom | [[Category: Wasney G]] | ||
[[Category: Wasney | [[Category: Weigelt J]] | ||
[[Category: Weigelt | [[Category: Wernimont AK]] | ||
[[Category: Wernimont | [[Category: Zhao Y]] | ||
[[Category: Zhao | |||
Latest revision as of 08:38, 30 October 2024
Crystal structure of Plasmodium falciparum pyrroline carboxylate reductase (MAL13P1.284) with NADP bound
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