2z3t: Difference between revisions

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==Crystal Structure of Substrate Free Cytochrome P450 StaP (CYP245A1)==
==Crystal Structure of Substrate Free Cytochrome P450 StaP (CYP245A1)==
<StructureSection load='2z3t' size='340' side='right' caption='[[2z3t]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2z3t' size='340' side='right'caption='[[2z3t]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2z3t]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp._tp-a0274 Streptomyces sp. tp-a0274]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z3T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z3T FirstGlance]. <br>
<table><tr><td colspan='2'>[[2z3t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_sp._TP-A0274 Streptomyces sp. TP-A0274]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z3T FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2z3u|2z3u]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">staP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=171258 Streptomyces sp. TP-A0274])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z3t OCA], [https://pdbe.org/2z3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z3t RCSB], [https://www.ebi.ac.uk/pdbsum/2z3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z3t ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z3t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z3t RCSB], [http://www.ebi.ac.uk/pdbsum/2z3t PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/Q83WG3_9ACTN Q83WG3_9ACTN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z3/2z3t_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z3/2z3t_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z3t ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2z3t" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Cytochrome P450|Cytochrome P450]]
*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Streptomyces sp. tp-a0274]]
[[Category: Large Structures]]
[[Category: Asamizu, S.]]
[[Category: Streptomyces sp. TP-A0274]]
[[Category: Makino, M.]]
[[Category: Asamizu S]]
[[Category: Nagano, S.]]
[[Category: Makino M]]
[[Category: Onaka, H.]]
[[Category: Nagano S]]
[[Category: Shiro, Y.]]
[[Category: Onaka H]]
[[Category: Sugimoto, H.]]
[[Category: Shiro Y]]
[[Category: Cytochrome p450]]
[[Category: Sugimoto H]]
[[Category: Heme-enzyme]]
[[Category: Monoxygenase]]
[[Category: Oxidoreductase]]
[[Category: Oxydoreductase]]