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==PHAGE LAMBDA INTDBD1-64 COMPLEX WITH P PRIME 2 DNA==
 
<StructureSection load='2wcc' size='340' side='right' caption='[[2wcc]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
==phage lambda IntDBD1-64 complex with p prime 2 DNA==
<StructureSection load='2wcc' size='340' side='right'caption='[[2wcc]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wcc]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WCC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WCC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wcc]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteriophage_lambda Bacteriophage lambda]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WCC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WCC FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1z1g|1z1g]], [[1z1b|1z1b]], [[1kjk|1kjk]], [[1z19|1z19]], [[1ae9|1ae9]], [[1m97|1m97]], [[1p7d|1p7d]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1z1g|1z1g]], [[1z1b|1z1b]], [[1kjk|1kjk]], [[1z19|1z19]], [[1ae9|1ae9]], [[1m97|1m97]], [[1p7d|1p7d]]</div></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wcc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wcc RCSB], [http://www.ebi.ac.uk/pdbsum/2wcc PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wcc OCA], [https://pdbe.org/2wcc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wcc RCSB], [https://www.ebi.ac.uk/pdbsum/2wcc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wcc ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/VINT_LAMBD VINT_LAMBD]] Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/2wcc_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/2wcc_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wcc ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2wcc" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Phage integrase|Phage integrase]]
*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]]
*[[Resolvase|Resolvase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Enterobacteria phage lambda]]
[[Category: Bacteriophage lambda]]
[[Category: Clubb, R T.]]
[[Category: Large Structures]]
[[Category: Fadeev, E A.]]
[[Category: Clubb, R T]]
[[Category: Sam, M D.]]
[[Category: Fadeev, E A]]
[[Category: Sam, M D]]
[[Category: Dna integration]]
[[Category: Dna integration]]
[[Category: Dna recombination]]
[[Category: Dna recombination]]
Retrieved from "https://proteopedia.org/2wcc"