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==Crystal Structure of the Snow Flea Antifreeze Protein==
==Crystal Structure of the Snow Flea Antifreeze Protein==
<StructureSection load='2pne' size='340' side='right' caption='[[2pne]], [[Resolution|resolution]] 0.98&Aring;' scene=''>
<StructureSection load='2pne' size='340' side='right'caption='[[2pne]], [[Resolution|resolution]] 0.98&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2pne]] is a 1 chain structure. The December 2009 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Antifreeze Proteins''  by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2009_12 10.2210/rcsb_pdb/mom_2009_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PNE FirstGlance]. <br>
<table><tr><td colspan='2'>[[2pne]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hypogastrura_harveyi Hypogastrura harveyi]. The December 2009 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Antifreeze Proteins''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2009_12 10.2210/rcsb_pdb/mom_2009_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PNE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PNE FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pne OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pne RCSB], [http://www.ebi.ac.uk/pdbsum/2pne PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.98&#8491;</td></tr>
<table>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pne OCA], [https://pdbe.org/2pne PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pne RCSB], [https://www.ebi.ac.uk/pdbsum/2pne PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pne ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q38PT6_9HEXA Q38PT6_9HEXA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pn/2pne_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pn/2pne_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pne ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2pne" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Antifreeze protein|Antifreeze protein]]
*[[Antifreeze protein 3D structures|Antifreeze protein 3D structures]]
*[[Sandox 2pne|Sandox 2pne]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Antifreeze Proteins]]
[[Category: Antifreeze Proteins]]
[[Category: Hypogastrura harveyi]]
[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Dashnau, J.]]
[[Category: Dashnau J]]
[[Category: Gates, Z P.]]
[[Category: Gates ZP]]
[[Category: Kossiakoff, A A.]]
[[Category: Kent SBH]]
[[Category: Kurutz, J.]]
[[Category: Kossiakoff AA]]
[[Category: Pentelute, B L.]]
[[Category: Kurutz J]]
[[Category: S B.H., Kent.]]
[[Category: Pentelute BL]]
[[Category: Tereshko, V.]]
[[Category: Tereshko V]]
[[Category: Vaderkooi, J M.]]
[[Category: Vaderkooi JM]]
[[Category: Antifreeze protein]]
[[Category: Chemical protein synthesis]]
[[Category: Native chemical ligation]]
Retrieved from "https://proteopedia.org/2pne"