1scz: Difference between revisions
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==Improved structural model for the catalytic domain of E.coli dihydrolipoamide succinyltransferase== | ==Improved structural model for the catalytic domain of E.coli dihydrolipoamide succinyltransferase== | ||
<StructureSection load='1scz' size='340' side='right' caption='[[1scz]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='1scz' size='340' side='right'caption='[[1scz]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1scz]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1scz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SCZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SCZ FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1scz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1scz OCA], [https://pdbe.org/1scz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1scz RCSB], [https://www.ebi.ac.uk/pdbsum/1scz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1scz ProSAT]</span></td></tr> | |||
<tr | </table> | ||
== Function == | |||
<table> | [https://www.uniprot.org/uniprot/ODO2_ECOLI ODO2_ECOLI] The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sc/1scz_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sc/1scz_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1scz ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[2- | *[[2-oxoglutarate dehydrogenase 3D structures|2-oxoglutarate dehydrogenase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli K-12]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arabashi | [[Category: Arabashi A]] | ||
[[Category: Bunzel | [[Category: Bunzel B]] | ||
[[Category: Carson | [[Category: Carson M]] | ||
[[Category: DeLucas | [[Category: DeLucas L]] | ||
[[Category: Gray | [[Category: Gray R]] | ||
[[Category: Huang | [[Category: Huang W-Y]] | ||
[[Category: Johnson | [[Category: Johnson D]] | ||
[[Category: Li | [[Category: Li S]] | ||
[[Category: Lin | [[Category: Lin G]] | ||
[[Category: Lu | [[Category: Lu S]] | ||
[[Category: Luan | [[Category: Luan C-H]] | ||
[[Category: Luo | [[Category: Luo D]] | ||
[[Category: Luo | [[Category: Luo M]] | ||
[[Category: Nagy | [[Category: Nagy L]] | ||
[[Category: Pruett | [[Category: Pruett P]] | ||
[[Category: Qiu | [[Category: Qiu S]] | ||
[[Category: Schormann | [[Category: Schormann N]] | ||
[[Category: Symersky | [[Category: Symersky J]] | ||
[[Category: Tsao | [[Category: Tsao J]] | ||
[[Category: Zhang | [[Category: Zhang Z]] | ||
