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[[Image:1h1j.jpg|left|200px]]


{{Structure
==The SAP domain is a DNA-Binding Domain Capable of Binding S/MAR DNA==
|PDB= 1h1j |SIZE=350|CAPTION= <scene name='initialview01'>1h1j</scene>
<StructureSection load='1h1j' size='340' side='right'caption='[[1h1j]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1h1j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H1J FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1j OCA], [https://pdbe.org/1h1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h1j RCSB], [https://www.ebi.ac.uk/pdbsum/1h1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h1j ProSAT]</span></td></tr>
}}
</table>
 
== Function ==
'''THE SAP DOMAIN IS A DNA-BINDING DOMAIN CAPABLE OF BINDING S/MAR DNA'''
[https://www.uniprot.org/uniprot/THO1_YEAST THO1_YEAST] Unknown; suppressor of the transcriptional defect of HPR1 by overexpression.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
1H1J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1J OCA].  
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h1/1h1j_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h1j ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Bycroft M]]
[[Category: Bycroft, M.]]
[[Category: Freund SMV]]
[[Category: Freund, S M.V.]]
[[Category: Jacobsen JOB]]
[[Category: Jacobsen, J O.B.]]
[[Category: dna binding]]
[[Category: sap domain]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:30:51 2008''

Latest revision as of 11:26, 27 March 2024

The SAP domain is a DNA-Binding Domain Capable of Binding S/MAR DNA

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