1uc6: Difference between revisions

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==Solution Structure of the Carboxyl Terminal Domain of the Ciliary Neurotrophic Factor Receptor==
==Solution Structure of the Carboxyl Terminal Domain of the Ciliary Neurotrophic Factor Receptor==
<StructureSection load='1uc6' size='340' side='right' caption='[[1uc6]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''>
<StructureSection load='1uc6' size='340' side='right'caption='[[1uc6]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1uc6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UC6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1uc6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UC6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UC6 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uc6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uc6 RCSB], [http://www.ebi.ac.uk/pdbsum/1uc6 PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<table>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uc6 OCA], [https://pdbe.org/1uc6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uc6 RCSB], [https://www.ebi.ac.uk/pdbsum/1uc6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uc6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CNTFR_HUMAN CNTFR_HUMAN] Binds to CNTF. The alpha subunit provides the receptor specificity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uc/1uc6_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uc/1uc6_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uc6 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1uc6" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: He, W.]]
[[Category: Large Structures]]
[[Category: Ip, N Y.]]
[[Category: He W]]
[[Category: Ke, G.]]
[[Category: Ip NY]]
[[Category: Man, D.]]
[[Category: Ke G]]
[[Category: Smith, D K.]]
[[Category: Man D]]
[[Category: Sze, K H.]]
[[Category: Smith DK]]
[[Category: Zhu, G.]]
[[Category: Sze KH]]
[[Category: Ciliary neurotrophic factor]]
[[Category: Zhu G]]
[[Category: Cytokine]]
[[Category: Cytokine receptor]]
[[Category: Fibronectin type iii domain-like topology]]
[[Category: Leukemia inhibitory factor]]
[[Category: Protein binding]]
[[Category: Seven beta-strand]]
[[Category: Two anti-parallel beta-sheet]]

Latest revision as of 23:50, 27 December 2023

Solution Structure of the Carboxyl Terminal Domain of the Ciliary Neurotrophic Factor Receptor

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