2cmn: Difference between revisions

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==A PROXIMAL ARGININE RESIDUE IN THE SWITCHING MECHANISM OF THE FIXL OXYGEN SENSOR==
 
<StructureSection load='2cmn' size='340' side='right' caption='[[2cmn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
==A Proximal Arginine Residue in the Switching Mechanism of the FixL Oxygen Sensor==
<StructureSection load='2cmn' size='340' side='right'caption='[[2cmn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cmn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bradyrhizobium_japonicum Bradyrhizobium japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CMN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CMN FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cmn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bradyrhizobium_japonicum Bradyrhizobium japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CMN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CMN FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dp6|1dp6]], [[1dp8|1dp8]], [[1dp9|1dp9]], [[1drm|1drm]], [[1lsv|1lsv]], [[1lsw|1lsw]], [[1lsx|1lsx]], [[1lt0|1lt0]], [[1xj2|1xj2]], [[1xj3|1xj3]], [[1xj4|1xj4]], [[1xj6|1xj6]], [[1y28|1y28]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cmn OCA], [https://pdbe.org/2cmn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cmn RCSB], [https://www.ebi.ac.uk/pdbsum/2cmn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cmn ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cmn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cmn RCSB], [http://www.ebi.ac.uk/pdbsum/2cmn PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/FIXL_BRADU FIXL_BRADU] Putative oxygen sensor; modulates the activity of FixJ, a transcriptional activator of nitrogen fixation fixK gene. FixL probably acts as a kinase that phosphorylates FixJ.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cm/2cmn_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cm/2cmn_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cmn ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2cmn" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bradyrhizobium japonicum]]
[[Category: Bradyrhizobium japonicum]]
[[Category: Histidine kinase]]
[[Category: Large Structures]]
[[Category: Brautigam, C A.]]
[[Category: Brautigam CA]]
[[Category: Caceres, A I.]]
[[Category: Caceres AI]]
[[Category: Gilles-Gonzalez, M A.]]
[[Category: Gilles-Gonzalez M-A]]
[[Category: Gonzalez, C.]]
[[Category: Gonzalez C]]
[[Category: Machius, M.]]
[[Category: Machius M]]
[[Category: Sousa, E H.Silva.]]
[[Category: Silva Sousa EH]]
[[Category: Tomchick, D R.]]
[[Category: Tomchick DR]]
[[Category: Inner membrane]]
[[Category: Nitrogen fixation]]
[[Category: Sensory transduction]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Two- component system]]