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==NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.==
==NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.==
<StructureSection load='2b3w' size='340' side='right' caption='[[2b3w]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2b3w' size='340' side='right'caption='[[2b3w]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2b3w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B3W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B3W FirstGlance]. <br>
<table><tr><td colspan='2'>[[2b3w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B3W FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ybiA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b3w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b3w RCSB], [http://www.ebi.ac.uk/pdbsum/2b3w PDBsum], [http://www.topsan.org/Proteins/NESGC/2b3w TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b3w OCA], [https://pdbe.org/2b3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b3w RCSB], [https://www.ebi.ac.uk/pdbsum/2b3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b3w ProSAT], [https://www.topsan.org/Proteins/NESGC/2b3w TOPSAN]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RIBX_ECOLI RIBX_ECOLI] Catalyzes the hydrolysis of the N-glycosidic bond in the first two intermediates of riboflavin biosynthesis, which are highly reactive metabolites, yielding relatively innocuous products. Thus, can divert a surplus of harmful intermediates into relatively harmless products and pre-empt the damage these intermediates would otherwise do. Helps maintain flavin levels. May act on other substrates in vivo. Has no activity against GTP, nucleoside monophosphates or ADP-ribose (PubMed:25431972). Is Required for swarming motility (PubMed:17122336).<ref>PMID:17122336</ref> <ref>PMID:25431972</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b3/2b3w_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b3/2b3w_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b3w ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Acton, T B.]]
[[Category: Large Structures]]
[[Category: Cort, J R.]]
[[Category: Acton TB]]
[[Category: Kennedy, M A.]]
[[Category: Cort JR]]
[[Category: Montelione, G T.]]
[[Category: Kennedy MA]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Montelione GT]]
[[Category: Ramelot, T A.]]
[[Category: Ramelot TA]]
[[Category: Shih, L Y.]]
[[Category: Shih LY]]
[[Category: Xiao, R.]]
[[Category: Xiao R]]
[[Category: Cog 3236]]
[[Category: Et24]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Unknown function]]
[[Category: Ybia]]
Retrieved from "https://proteopedia.org/2b3w"