1ih2: Difference between revisions

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[[Image:1ih2.gif|left|200px]]


{{Structure
==Crystal Structure of GGBr5CGBr5CC==
|PDB= 1ih2 |SIZE=350|CAPTION= <scene name='initialview01'>1ih2</scene>, resolution 2.8&Aring;
<StructureSection load='1ih2' size='340' side='right'caption='[[1ih2]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
|SITE=
== Structural highlights ==
|LIGAND=
<table><tr><td colspan='2'>[[1ih2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IH2 FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CBR:5-BROMO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>CBR</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ih2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ih2 OCA], [https://pdbe.org/1ih2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ih2 RCSB], [https://www.ebi.ac.uk/pdbsum/1ih2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ih2 ProSAT]</span></td></tr>
 
</table>
'''Crystal Structure of GGBr5CGBr5CC'''
__TOC__
 
</StructureSection>
 
[[Category: Large Structures]]
==Overview==
[[Category: Henderson K]]
The transition between B- and A-DNA was first observed nearly 50 years ago. We have now mapped this transformation through a set of single-crystal structures of the sequence d(GGCGCC)2, with various intermediates being trapped by methylating or brominating the cytosine bases. The resulting pathway progresses through 13 conformational steps, with a composite structure that pairs A-nucleotides with complementary B-nucleotides serving as a distinct transition intermediate. The details of each step in the conversion of B- to A-DNA are thus revealed at the atomic level, placing intermediates for this and other sequences in the context of a common pathway.
[[Category: Ho PS]]
 
[[Category: Vargason JM]]
==About this Structure==
1IH2 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH2 OCA].  
 
==Reference==
A crystallographic map of the transition from B-DNA to A-DNA., Vargason JM, Henderson K, Ho PS, Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7265-70. Epub 2001 Jun 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11390969 11390969]
[[Category: Protein complex]]
[[Category: Henderson, K.]]
[[Category: Ho, P S.]]
[[Category: Vargason, J M.]]
[[Category: b to a dna transition]]
[[Category: dna transition]]
[[Category: structural transition]]
 
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Retrieved from "https://proteopedia.org/1ih2"