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==Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS - Trp peptide structure==
==Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS - Trp peptide structure==
<StructureSection load='2wa9' size='340' side='right' caption='[[2wa9]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='2wa9' size='340' side='right'caption='[[2wa9]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wa9]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WA9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wa9]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WA9 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mbu|1mbu]], [[1lzw|1lzw]], [[2w9r|2w9r]], [[1mbv|1mbv]], [[1mg9|1mg9]], [[1r6o|1r6o]], [[1r6q|1r6q]], [[1mbx|1mbx]], [[2wa8|2wa8]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wa9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wa9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wa9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wa9 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wa9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wa9 OCA], [https://pdbe.org/2wa9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wa9 RCSB], [https://www.ebi.ac.uk/pdbsum/2wa9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wa9 ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CLPS_ECOLI CLPS_ECOLI] Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wa/2wa9_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wa/2wa9_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wa9 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2wa9" style="background-color:#fffaf0;"></div>
==See Also==
*[[ATP-dependent Clp protease adaptor protein 3D structures|ATP-dependent Clp protease adaptor protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Albrecht, R.]]
[[Category: Large Structures]]
[[Category: Dougan, D A.]]
[[Category: Albrecht R]]
[[Category: Kralik, S M.]]
[[Category: Dougan DA]]
[[Category: Schuenemann, V J.]]
[[Category: Kralik SM]]
[[Category: Spall, S K.]]
[[Category: Schuenemann VJ]]
[[Category: Truscott, K N.]]
[[Category: Spall SK]]
[[Category: Zeth, K.]]
[[Category: Truscott KN]]
[[Category: Clpa]]
[[Category: Zeth K]]
[[Category: Clpp]]
[[Category: Clp]]
[[Category: N-end rule recognition]]
[[Category: Peptide-binding protein]]

Latest revision as of 10:10, 9 May 2024

Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS - Trp peptide structure

2wa9, resolution 2.90Å

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