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==CRYSTAL STRUCTURE OF THE SECOND PDZ DOMAIN OF NUMB-BINDING PROTEIN 2==
 
<StructureSection load='2vwr' size='340' side='right' caption='[[2vwr]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
==Crystal structure of the second pdz domain of numb-binding protein 2==
<StructureSection load='2vwr' size='340' side='right'caption='[[2vwr]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vwr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VWR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VWR FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vwr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VWR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VWR FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vwr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vwr RCSB], [http://www.ebi.ac.uk/pdbsum/2vwr PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
<table>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vwr OCA], [https://pdbe.org/2vwr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vwr RCSB], [https://www.ebi.ac.uk/pdbsum/2vwr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vwr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LNX2_HUMAN LNX2_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vw/2vwr_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vw/2vwr_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vwr ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bountra, C.]]
[[Category: Arrowsmith CH]]
[[Category: Burgess-Brown, N.]]
[[Category: Bountra C]]
[[Category: Delft, F Von.]]
[[Category: Burgess-Brown N]]
[[Category: Doyle, D.]]
[[Category: Doyle D]]
[[Category: Edwards, A.]]
[[Category: Edwards A]]
[[Category: Elkins, J M.]]
[[Category: Elkins JM]]
[[Category: Filippakopoulos, P.]]
[[Category: Filippakopoulos P]]
[[Category: Guo, K.]]
[[Category: Guo K]]
[[Category: Oppermann, U.]]
[[Category: Oppermann U]]
[[Category: Pike, A C.W.]]
[[Category: Pike ACW]]
[[Category: Roos, A K.]]
[[Category: Roos AK]]
[[Category: Wikstom, M.]]
[[Category: Wikstom M]]
[[Category: Yue, W W.]]
[[Category: Yue WW]]
[[Category: Casp8 protein-binding]]
[[Category: Von Delft F]]
[[Category: Ligand of numb protein]]
[[Category: Lnx2_human]]
[[Category: Metal-binding]]
[[Category: Protein-binding]]
[[Category: Ring finger protein 1]]
[[Category: Zinc-finger]]
Retrieved from "https://proteopedia.org/2vwr"