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==STRUCTURAL AND MECHANISTIC INSIGHTS INTO HELICOBACTER PYLORI NIKR FUNCTION==
 
<StructureSection load='2wvc' size='340' side='right' caption='[[2wvc]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
==Structural and mechanistic insights into Helicobacter pylori NikR function==
<StructureSection load='2wvc' size='340' side='right'caption='[[2wvc]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wvc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WVC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wvc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WVC FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2caj|2caj]], [[2ca9|2ca9]], [[2cad|2cad]], [[2wvb|2wvb]], [[2wvd|2wvd]], [[2wve|2wve]], [[2wvf|2wvf]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wvc RCSB], [http://www.ebi.ac.uk/pdbsum/2wvc PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvc OCA], [https://pdbe.org/2wvc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wvc RCSB], [https://www.ebi.ac.uk/pdbsum/2wvc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wvc ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NIKR_HELPY NIKR_HELPY] Transcriptional regulator (Potential).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wv/2wvc_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wv/2wvc_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wvc ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2wvc" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori 26695]]
[[Category: Bahlawane, C.]]
[[Category: Large Structures]]
[[Category: Delay, C.]]
[[Category: Bahlawane C]]
[[Category: Dian, C.]]
[[Category: Delay C]]
[[Category: Fauquant, C.]]
[[Category: Dian C]]
[[Category: Michaud-Soret, I.]]
[[Category: Fauquant C]]
[[Category: Muller, C.]]
[[Category: Michaud-Soret I]]
[[Category: Reuse, H De.]]
[[Category: Muller C]]
[[Category: Round, A.]]
[[Category: Round A]]
[[Category: Schauer, K.]]
[[Category: Schauer K]]
[[Category: Terradot, L.]]
[[Category: Terradot L]]
[[Category: Dna-binding]]
[[Category: De Reuse H]]
[[Category: Metal-binding]]
[[Category: Metalloregulator]]
[[Category: Rhh]]
[[Category: Transcription]]
[[Category: Transcription factor]]
[[Category: Transcription regulation]]

Latest revision as of 10:17, 20 December 2023

Structural and mechanistic insights into Helicobacter pylori NikR function

2wvc, resolution 2.10Å

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