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==The antimicrobial peptidase lysostaphin from Staphylococcus simulans==
==The antimicrobial peptidase lysostaphin from Staphylococcus simulans==
<StructureSection load='4lxc' size='340' side='right' caption='[[4lxc]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
<StructureSection load='4lxc' size='340' side='right'caption='[[4lxc]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lxc]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LXC FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lxc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_simulans Staphylococcus simulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LXC FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qwy|1qwy]], [[2b0p|2b0p]], [[2b13|2b13]], [[2b44|2b44]], [[4bh5|4bh5]], [[1r77|1r77]], [[3it5|3it5]], [[3it7|3it7]], [[4qpb|4qpb]], [[4qp5|4qp5]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysostaphin Lysostaphin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.75 3.4.24.75] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lxc OCA], [https://pdbe.org/4lxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lxc RCSB], [https://www.ebi.ac.uk/pdbsum/4lxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lxc ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lxc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lxc RCSB], [http://www.ebi.ac.uk/pdbsum/4lxc PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/LSTP_STASI LSTP_STASI] Lyses staphylococcal cells by hydrolyzing the polyglycine interpeptide bridges of the peptidoglycan.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4lxc" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lysostaphin]]
[[Category: Large Structures]]
[[Category: Bardelang, P T.]]
[[Category: Staphylococcus simulans]]
[[Category: Bochtler, M.]]
[[Category: Bardelang PT]]
[[Category: Czapinska, H.]]
[[Category: Bochtler M]]
[[Category: Dahms, S O.]]
[[Category: Czapinska H]]
[[Category: Jagielska, E.]]
[[Category: Dahms SO]]
[[Category: James, R.]]
[[Category: Jagielska E]]
[[Category: Sabala, I.]]
[[Category: James R]]
[[Category: Sharpe, J A.]]
[[Category: Sabala I]]
[[Category: Than, M E.]]
[[Category: Sharpe JA]]
[[Category: Thomas, N R.]]
[[Category: Than ME]]
[[Category: Hydrolase]]
[[Category: Thomas NR]]
[[Category: Metallopeptidase]]
[[Category: Peptidase family m23]]
[[Category: Peptidoglycan]]
[[Category: Peptidoglycan hydrolase]]

Latest revision as of 16:27, 20 September 2023

The antimicrobial peptidase lysostaphin from Staphylococcus simulans

4lxc, resolution 3.50Å

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