2v58: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
==CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 1==
==CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 1==
<StructureSection load='2v58' size='340' side='right' caption='[[2v58]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='2v58' size='340' side='right'caption='[[2v58]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2v58]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V58 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V58 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2v58]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V58 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V58 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LZJ:6-(2,6-DIBROMOPHENYL)PYRIDO[2,3-D]PYRIMIDINE-2,7-DIAMINE'>LZJ</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2j9g|2j9g]], [[2vr1|2vr1]], [[1k69|1k69]], [[2gpw|2gpw]], [[1dv1|1dv1]], [[1bnc|1bnc]], [[2gps|2gps]], [[1dv2|1dv2]], [[2v59|2v59]], [[2v5a|2v5a]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LZJ:6-(2,6-DIBROMOPHENYL)PYRIDO[2,3-D]PYRIMIDINE-2,7-DIAMINE'>LZJ</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Biotin_carboxylase Biotin carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.14 6.3.4.14] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v58 OCA], [https://pdbe.org/2v58 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v58 RCSB], [https://www.ebi.ac.uk/pdbsum/2v58 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v58 ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v58 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v58 RCSB], [http://www.ebi.ac.uk/pdbsum/2v58 PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/ACCC_ECOLI ACCC_ECOLI] This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 16: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2v58" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Biotin carboxylase|Biotin carboxylase]]
*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Biotin carboxylase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Miller, J R.]]
[[Category: Large Structures]]
[[Category: Mochalkin, I.]]
[[Category: Miller JR]]
[[Category: Antibacterial]]
[[Category: Mochalkin I]]
[[Category: Atp-binding]]
[[Category: Bacterial]]
[[Category: Biotin]]
[[Category: Biotin carboxylase]]
[[Category: Fa]]
[[Category: Fatty acid biosynthesis]]
[[Category: Inhibitor]]
[[Category: Ligase]]
[[Category: Lipid synthesis]]
[[Category: Nucleotide-binding]]
Retrieved from "https://proteopedia.org/2v58"