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==CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS RV0376C HOMOLOGUE FROM MYCOBACTERIUM SMEGMATIS==
 
<StructureSection load='2we8' size='340' side='right' caption='[[2we8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
==Crystal structure of Mycobacterium tuberculosis Rv0376c homologue from Mycobacterium smegmatis==
<StructureSection load='2we8' size='340' side='right'caption='[[2we8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2we8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WE8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WE8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2we8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WE8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WE8 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2we7|2we7]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xanthine_dehydrogenase Xanthine dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.1.4 1.17.1.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2we8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2we8 OCA], [https://pdbe.org/2we8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2we8 RCSB], [https://www.ebi.ac.uk/pdbsum/2we8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2we8 ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2we8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2we8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2we8 RCSB], [http://www.ebi.ac.uk/pdbsum/2we8 PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/A0QQG1_MYCS2 A0QQG1_MYCS2]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/we/2we8_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/we/2we8_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2we8 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Xanthine dehydrogenase|Xanthine dehydrogenase]]
*[[Xanthine dehydrogenase 3D structures|Xanthine dehydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Mycobacterium smegmatis]]
[[Category: Large Structures]]
[[Category: Xanthine dehydrogenase]]
[[Category: Mycolicibacterium smegmatis MC2 155]]
[[Category: Cho, H J.]]
[[Category: Cho HJ]]
[[Category: Kang, B S.]]
[[Category: Kang BS]]
[[Category: Oxidoreductase]]

Latest revision as of 15:53, 13 December 2023

Crystal structure of Mycobacterium tuberculosis Rv0376c homologue from Mycobacterium smegmatis

2we8, resolution 2.30Å

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