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==Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)==
==Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)==
<StructureSection load='2z36' size='340' side='right' caption='[[2z36]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='2z36' size='340' side='right'caption='[[2z36]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2z36]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Nonomuraea_recticatena Nonomuraea recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z36 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2z36]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nonomuraea_recticatena Nonomuraea recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z36 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">moxA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46178 Nonomuraea recticatena])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z36 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z36 RCSB], [http://www.ebi.ac.uk/pdbsum/2z36 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z36 OCA], [https://pdbe.org/2z36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z36 RCSB], [https://www.ebi.ac.uk/pdbsum/2z36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z36 ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q2L6S8_9ACTN Q2L6S8_9ACTN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z3/2z36_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z3/2z36_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z36 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2z36" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Nonomuraea recticatena]]
[[Category: Nonomuraea recticatena]]
[[Category: Arisawa, A.]]
[[Category: Arisawa A]]
[[Category: Fujii, T.]]
[[Category: Fujii T]]
[[Category: Fujii, Y.]]
[[Category: Fujii Y]]
[[Category: Tamura, T.]]
[[Category: Tamura T]]
[[Category: Yasutake, Y.]]
[[Category: Yasutake Y]]
[[Category: Cyp105]]
[[Category: Oxidoreductase]]
[[Category: P450]]

Latest revision as of 10:41, 30 April 2025

Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)

2z36, resolution 2.80Å

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